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Hassle-free Microscopy Manager


Hassle-free Microscopy Manager

For all Open-Architecture Advanced Microscopy Developers

For all Open-Architecture Advanced Microscopy Developers

What Once Took Many Cards and Experts, Now HMM Does All

What Once Took Many Cards and Experts, Now HMM Does All

TLI-HMM Integrates 4Chs 1GS/s High-speed Data Acquisition, In-Line processing,    

Sync Signal, and Control Software in One Platform

TLI-HMM Integrates 4Chs 1GS/s High-speed Data Acquisition, In-Line processing, Sync Signal, and Control Software in One Platform


HMM for Laser Scanning Microscopies

HMM for Laser Scanning Microscopies

Remarkable System Simplification with TLI HMM-SC Design for Research and Prototyping

Remarkable System Simplification with TLI HMM-SC Design for Research and Prototyping

Build Video Cube Rate Multiphoton/Confocal Microscope with TLI-HMM-SC

Build Video Cube Rate Multiphoton/Confocal Microscope with TLI-HMM-SC

Build Circular Dichroism Microscope​ with TLI-HMM-SC

Build Circular Dichroism Microscope with TLI-HMM-SC

Build FLIM Microscope with TLI-HMM-SC

Build FLIM Microscope with 
TLI-HMM-SC

Build FLIM Multimodality Microscope with TLI-HMM-SC

Build FLIM Multimodality Microscope with TLI-HMM-SC

Build FLIM Multimodality Microscope with TLI-HMM-SC

Build FLIM Multimodality Microscope with TLI-HMM-SC

Multiphoton-Microscope with TLI-HMM-SC 

High Sampling Rate Brings Better Image Quality 

Multiphoton-Microscope with TLI-HMM-SC 
High Sampling Rate Brings Better Image Quality 

Video Rate Multiphoton-Microscope with TLI-HMM-SC 

High-Speed, High Resolution, no Compromise

Video Rate Multiphoton-Microscope with TLI-HMM-SC 
High-Speed, High Resolution,
 no Compromise

Customized Algorithm Workflow with TLI-HMM-SC 

Customized Algorithm Workflow with TLI-HMM-SC 

Integrate TLI-HMM with GPU 

Integrate TLI-HMM with GPU 

Customized Algorithm Example : Precise Peak Detection

Customized Algorithm Example : Precise Peak Detection

Customized Algorithm Example : Time Resolved SHG/THG and Fluorescence Image

Customized Algorithm Example : Time Resolved SHG/THG and Fluorescence Image

Unique Advantages of the TLI-HMM-SC

Unique Advantages of the 
TLI-HMM-SC

  1. Plug-and-Play Integration – A single PCIe card consolidates high-speed signal acquisition, scanner control, and real-time image reconstruction, eliminating the need for multiple hardware modules and reducing integration time from months to minutes.
  2. Ultra-compact, Engineering-oriented Form Factor – The card-level design drastically reduces system footprint, making it especially suitable as a prototyping platform for next-generation microscopy development, where flexibility and rapid iteration are critical.
  3. Low Host Computer Requirements – With FPGA-based in-line processing, most heavy computation is handled on-board, allowing operation with standard PCs instead of costly high-performance workstations.
  4. True Real-time Performance – High-throughput (1 GS/s, 16-bit) acquisition combined with low-latency FPGA pipelines enables immediate feedback, critical for live imaging, fast scanning, and time-sensitive experiments.
  5. Multi-technology Compatibility – The architecture is inherently modular, supporting confocal, multiphoton, STED, TIRF, SNOM, FLIM, Chiral Dichroism, and  photoacoustic microscopy on the same unified platform.
  6. Scalability and Future-proof Design – A reconfigurable FPGA core and microSD-based firmware updates allow continuous upgrades, ensuring long-term adaptability without hardware replacement.
  7. Researcher-centric Workflow – By removing the burden of cross-device integration and synchronization, scientists can focus on optical innovation and biological discovery, not engineering bottlenecks.
  1. Plug-and-Play Integration – A single PCIe card consolidates high-speed signal acquisition, scanner control, and real-time image reconstruction, eliminating the need for multiple hardware modules and reducing integration time from months to minutes.
  2. Ultra-compact, Engineering-oriented Form Factor – The card-level design drastically reduces system footprint, making it especially suitable as a prototyping platform for next-generation microscopy development, where flexibility and rapid iteration are critical.
  3. Low Host Computer Requirements – With FPGA-based in-line processing, most heavy computation is handled on-board, allowing operation with standard PCs instead of costly high-performance workstations.
  4. True Real-time Performance – High-throughput (1 GS/s, 16-bit) acquisition combined with low-latency FPGA pipelines enables immediate feedback, critical for live imaging, fast scanning, and time-sensitive experiments.
  5. Multi-technology Compatibility – The architecture is inherently modular, supporting confocal, multiphoton, STED, TIRF, SNOM, FLIM, Chiral Dichroism, and  photoacoustic microscopy on the same unified platform.
  6. Scalability and Future-proof Design – A reconfigurable FPGA core and microSD-based firmware updates allow continuous upgrades, ensuring long-term adaptability without hardware replacement.
  7. Researcher-centric Workflow – By removing the burden of cross-device integration and synchronization, scientists can focus on optical innovation and biological discovery, not engineering bottlenecks.