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Omni Cell® Imager (OCI)

Unlock the Full Potential of Cell Imaging

It’s time to make a change

Imaging across modalities is critical—but switching between BF, DF, PC, and DIC often wastes time and introduces errors. And when new, advanced imaging modes not previously available (e.g., fused and quantitative phase imaging) are added——these challenges multiply. Cell imaging should be flexible, precise, and intuitive—but too often, it’s not. Researchers are forced to manually switch modes, swap components, realign samples, recalibrate systems, and lose valuable time in the process. The Omni Cell Imager is built to change that. 


Redefine what's possible in multimodal cell imaging

Omni Cell Imager (OCI): a cutting-edge, standalone, software-defined system designed to eliminate both the technical obstacles and day-to-day hassles of cell imaging. Powered by TLI's proprietary Programoptics paradigm and advanced spatial light modulators (SLMs) algorithms, OCI meets the diverse demands of cellular and bio-tissue research. Its unmatched versatility, precision, and performance bring seamless automation and AI connection withing a single workflow.

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Why Omni Cell Imager - Key Features & Benefits

    • Seamless Multimodal Imaging
      • Observe the same sample region of interest (ROI) in Brightfield (BF), Darkfield (DF), Phase Contrast (PC), and DIC, simultaneously.
      •  → Save time, reduce alignment errors, and gain richer data with minimal adjustment.
    • Fused Imaging Technology​
      • Automatically superimposing selected and weighted modes into a single content-rich image. 
      • → Accelerate AI analysis, reduce manual labeling, and improve segmentation accuracy.
    • Programmable Phase Control (0 –2π)
      • Adjust phase shifts with 0.05π precision to optimize PC/DIC contrast for various kinds of samples.
      • → Reveal subtle details in tissues and cells—ideal for quantitative phase imaging.
    • AI-Driven Optimization
      • Phase and contrast settings adjust dynamically for each sample.
      • → Ensure image quality consistency across diverse biological materials—no expert tuning needed.
    • Long-Term, Live Imaging Ready
      • Capture dynamic changes over hours or days with high stability.
      • → Monitor cell migration, division, or interactions in real time.
    • Programmable and Software-Defined Flexibility
      • All functionalities, including imaging parameters and phase adjustments, are software-defined and programmable.
    • Remote Control and Collaboration
      • Easily control and operate OCI remotely, enabling collaborative research across locations.
      • Ideal for shared facilities, multi-site studies, or remote observations.

Who It's For & Where It Fits

Perfect for:

  • Stem cell researchers tracking morphology and subcellular structural changes over time
  • Pathologists seeking richer contrast without staining
  • AI imaging labs training models with content-rich fused image data
  • Shared facilities requiring remote access and reproducibility
  • OCI is the imaging companion for teams pushing the boundaries of live cell observation, content-rich screening, and diagnostic imaging workflows.

Redefining the Workflow and Standard in Cell Imaging

The Omni Cell Imager (OCI) marks a significant advancement in cell imaging technology. Combining seamless multimodal imaging, precise phase control, advanced fused imaging, and AI-assisted optimization, OCI offers a powerful yet user-friendly solution for modern research needs. It is designed to help scientists overcome both technical barriers and everyday workflow hassles. Whether you're investigating complex cellular dynamics, analyzing bio-tissues, or implementing automated, AI-guided routines, OCI delivers the flexibility, accuracy, and performance to support and accelerate your scientific discoveries.

Experience the Future of Cell Imaging Today

Contact us to learn more about the Omni Cell Imager and how it can transform your research capabilities.

​Microscope Type
  • Transmission


Available Objectives

  • Standard : 10x Plan 
  • Option : 4x, 10x, 20x, 40x, 60x, 100x, RMS Threaded and Parfocal 45mm Objectives


 Turret  

  • Standard : Manual 5-Pos Turret with RMS Thread
  • Option :  Motorized 5-Pos Turret with RMS Thread


XY Stage


  • Option : Manual XY Stage, Motorized XY Stage 

 
Z Stage

  • Standard : Manual Z Stage
  • Option : Motorized Z Stage 

 
Laser Parameters

  • Wavelength : 638 nm 
  • Max Power : 180 mW
  • Power Adjustment : 0 - 100%

Field of View (FOV)

  • 1 mm x 1.5 mm @ 10x Objective  

 
Imaging Camera


  • Camera Mount : C-mount Adaptor 
  • Pixels : 1920 x 1200 

Imaging Modes

  • Bright Field (BF), Dark Field (DF)，Phase Contrast (PC), Differential Interference Contrast (DIC)，Fused Mode  

Adjustable Phase Difference

  • 0.05 pi (@PC and DIC Modes)

Display Modes

  • Single Mode, Multi-Mode

Saving Modes

  • Snap Shot, Scan Phase (PC and DIC Modes Only), Time-Lapsed, Record

Data Type

  • Tiff


Software

  • Standard : Standard Software, SDK Library
  • Option : Quantitative Phase Measurement, provide optimized image quality for further AI analysis

Connectors

  • USB x2

Power

  • 100 - 230 VAC



Publication in BiOSExpo SPIE, ​​Jan. 2025
See Programoptics in Action: Real-Time Cell Imaging for Therapy Applications
4 Modes. 1 Setup. Fully Programmed Multimodal Imaging
Reveal What Traditional Microscopes Miss
See the Unseen — 4 Optical Modes, 1 Seamless Platform


Contact us for more information​​

Unlock the Full Potential of Cell Imaging

It’s time to make a change

Imaging across modalities is critical—but switching between BF, DF, PC, and DIC often wastes time and introduces errors. And when new, advanced imaging modes not previously available (e.g., fused and quantitative phase imaging) are added——these challenges multiply. Cell imaging should be flexible, precise, and intuitive—but too often, it’s not. Researchers are forced to manually switch modes, swap components, realign samples, recalibrate systems, and lose valuable time in the process. The Omni Cell Imager is built to change that. 


Redefine what's possible in multimodal cell imaging

Omni Cell Imager (OCI): a cutting-edge, standalone, software-defined system designed to eliminate both the technical obstacles and day-to-day hassles of cell imaging. Powered by TLI's proprietary Programoptics paradigm and advanced spatial light modulators (SLMs) algorithms, OCI meets the diverse demands of cellular and bio-tissue research. Its unmatched versatility, precision, and performance bring seamless automation and AI connection withing a single workflow.


Contact Us

Why Omni Cell Imager - Key Features & Benefits  

Seamless Multimodal Imaging

  • Observe the same sample region of interest (ROI) in Brightfield (BF), Darkfield (DF), Phase Contrast (PC), and DIC, simultaneously. 
  • → Save time, reduce alignment errors, and gain richer data with minimal adjustment.

Fused Imaging Technology​

  • Automatically superimposing selected and weighted modes into a single content-rich image. 
  • → Accelerate AI analysis, reduce manual labeling, and improve segmentation accuracy.

Programmable Phase Control (0 –2π)

  • Adjust phase shifts with 0.05π precision to optimize PC/DIC contrast for various kinds of samples.
  • → Reveal subtle details in tissues and cells—ideal for quantitative phase imaging.

AI-Driven Optimization

  • Phase and contrast settings adjust dynamically for each sample.
  • → Ensure image quality consistency across diverse biological materials—no expert tuning needed.

Long-Term, Live Imaging Ready

  • Capture dynamic changes over hours or days with high stability.
  • → Monitor cell migration, division, or interactions in real time.

Programmable and Software-Defined Flexibility

  • All functionalities, including imaging parameters and phase adjustments, are software-defined and programmable.

Remote Control and Collaboration

  • Easily control and operate OCI remotely, enabling collaborative research across locations.
  • Ideal for shared facilities, multi-site studies, or remote observations.

Who It's For & Where It Fits

Perfect for:

  • Stem cell researchers tracking morphology and subcellular structural changes over time
  • Pathologists seeking richer contrast without staining
  • AI imaging labs training models with content-rich fused image data
  • Shared facilities requiring remote access and reproducibility
  • OCI is the imaging companion for teams pushing the boundaries of live cell observation, content-rich screening, and diagnostic imaging workflows.


Redefining the Workflow and Standard in Cell Imaging

The Omni Cell Imager (OCI) marks a significant advancement in cell imaging technology. Combining seamless multimodal imaging, precise phase control, advanced fused imaging, and AI-assisted optimization, OCI offers a powerful yet user-friendly solution for modern research needs. It is designed to help scientists overcome both technical barriers and everyday workflow hassles. Whether you're investigating complex cellular dynamics, analyzing bio-tissues, or implementing automated, AI-guided routines, OCI delivers the flexibility, accuracy, and performance to support and accelerate your scientific discoveries.

Experience the Future of Cell Imaging Today

Contact us to learn more about the Omni Cell Imager and how it can transform your research capabilities.

​Microscope Type
  • Transmission


Available Objectives

  • Standard : 10x Plan 
  • Option : 4x, 10x, 20x, 40x, 60x, 100x, RMS Threaded and Parfocal 45mm Objectives


Turret  

  • Standard : Manual 5-Pos Turret with RMS Thread
  • Option :  Motorized 5-Pos Turret with RMS Thread


XY Stage


  • Option : Manual XY Stage, Motorized XY Stage 

 
Z Stage

  • Standard : Manual Z Stage
  • Option : Motorized Z Stage 

 
Laser Parameters

  • Wavelength : 638 nm 
  • Max Power : 180 mW
  • Power Adjustment : 0 - 100%

Field of View (FOV)

  • 1 mm x 1.5 mm @ 10x Objective  

 
Imaging Camera


  • Camera Mount : C-mount Adaptor 
  • Pixels : 1920 x 1200 

Imaging Modes

  • Bright Field (BF), Dark Field (DF)，Phase Contrast (PC), Differential Interference Contrast (DIC)，Fused Mode  

Adjustable Phase Difference

  • 0.05 pi (@PC and DIC Modes)

Display Modes

  • Single Mode, Multi-Mode

Saving Modes

  • Snap Shot, Scan Phase (PC and DIC Modes Only), Time-Lapsed, Record

Data Type

  • Tiff


Software

  • Standard : Standard Software, SDK Library
  • Option : Quantitative Phase Measurement, provide optimized image quality for further AI analysis

Connectors

  • USB x2

Power

  • 100 - 230 VAC


Publication in BiOSExpo SPIE, ​​Jan. 2025
See Programoptics in Action: Real-Time Cell Imaging for Therapy Applications
4 Modes. 1 Setup. Fully Programmed Multimodal Imaging
Reveal What Traditional Microscopes Miss
See the Unseen — 4 Optical Modes, 1 Seamless Platform
Contact us for more information​​

Performance Showcase

 Prostate Cancer Images (BF, DF, PC, DIC)(40x)

ADSC Phase Scan PC Images 

Prostate Cancer Images (DF, PC, DIC, Fused Image)

One System. Both Phase Contrast and DIC. Image Quality You Can Trust

Achieve high-contrast PC and DIC imaging on a single, software-defined microscope — with clarity rivaling traditional optical systems.

Quantitative Phase Image (QPI) with BF, DF, PC, and DIC(40x)

~0.25s to take one QPI image, ~0.6s to take all images

 ADSC Images 

(BF, DF, PC, DIC)

ADSC Phase Scan PC Images 

Prostate Cancer Images 

(DF, PC, DIC, Fused Image)

Real-Time Recording of Exosome Brownian Motion

The Relationship Between GLCM Contrast and Phase 

Optimal Proportion Analysis of Fused Images

Software UI and Simultaneous Displaying 4 Modes(BF, DF, PC, DIC) of Images of The Same ROI

Software UI and Simultaneous Displaying 4 Modes(DF, PC, DIC, Fused Image) of Images of The Same ROI

Real-Time Recording of Exosome Brownian Motion

The Relationship Between GLCM Contrast and Phase 

Optimal Proportion Analysis of Fused Images

Software UI and Simultaneous Displaying 

4 Modes of Images of 

The Same ROI

Software UI and Simultaneous Displaying 

4 Modes of Images of 

The Same ROI